43		Dark Planet: Battle for Natrolis (Windows, 2002)
43		Project Earth: Starmageddon (Windows, 2002)
42		Outlive (Windows, 2001)
42		Far Gate (Windows, 2001)
40		Dynatech (DOS, 1992)
40		Battlevoid: Harbinger (Windows, 2016)
40		Overlord (DOS, 1990)

Notes: Games similar to Time of Defiance, Games like Time of Defiance, Nicely Crafted Entertainment Ltd, Strategy First, Inc., Windows, Strategy, Tactics, Sci-Fi, Futuristic, Persistent, Real-Time, PC, Game Similarities.