45		Agricultural Simulator 2011 (Windows, 2010)
44		Ports (Windows, 2011)
44		Under Development (Windows, 2011)
44		Stone Quarry Simulator (Windows, 2011)
44		Underground Mining Simulator (Windows, 2011)
44		Rescue Team (Windows, 2011)
44		Chloe's Dream Resort (Windows, 2011)
43		Agricultural Simulator 2013 (Windows, 2012)
43		Rescue Team 2 (Windows, 2012)
43		Farming Simulator 2013 (Windows, 2012)
42		My Time at Portia (Windows, 2018)
42		Fashion Craze (Windows, 2007)
42		Agricultural Simulator: Historical Farming (Windows, 2013)
41		Sim Chemist (Windows, 2006)
40		Firefighters: Airport Fire Department (Windows, 2016)
40		Professional Farmer: American Dream (Windows, 2017)
40		Farm Manager 2018 (Windows, 2018)
40		Flashing Lights: Police Fire EMS (Windows, 2018)
40		Real Farm (Windows, 2017)
40		The Partners (Windows, 2002)
40		Rescue Team 3 (Windows, 2015)
40		Shopping Centre Tycoon (Windows, 2005)
40		Snap-on presents Gearhead Garage: The Virtual Mechanic (Windows, 2000)
40		Luxury Liner Tycoon (Windows, 2005)
40		Professional Farmer 2017 (Windows, 2016)
40		Rescue Team 5 (Windows, 2015)
40		Forestry 2017: The Simulation (Windows, 2016)

Notes: Games similar to Heart's Medicine: Season One, Games like Heart's Medicine: Season One, GameHouse B.V., GameHouse, Inc., Windows, Simulation, Managerial, Business Simulation, Time Management, 3rd-person, Other, PC, Game Similarities.