74		Weird Science (Comedy, Romance, Sci-Fi, 1985)
70		Married to the Mob (Comedy, Crime, Romance, 1988)
69		Husbands and Wives (Comedy, Drama, Romance, 1992)
67		Date Night (Comedy, Crime, Romance, 2010)
67		The Seven Year Itch (Comedy, Romance, 1955)
67		Malèna (Comedy, Drama, Romance, 2000)
62		The 40-Year-Old Virgin (Comedy, Romance, 2005)
62		The Last Kiss (Comedy, Drama, Romance, 2006)
62		101 Reykjavík (Comedy, Romance, 2000)
62		Gun Shy (Comedy, Crime, Romance, 2000)
57		Class (Comedy, Drama, Romance, 1983)
57		Sixteen Candles (Comedy, Romance, 1984)
57		Easy Virtue (Comedy, Romance, 2008)
57		Mallrats (Comedy, Romance, 1995)
57		Chéri (Comedy, Drama, Romance, 2009)
57		Terror Tract (Comedy, Horror, Romance, 2000)
57		Knocked Up (Comedy, Romance, 2007)
57		Georgy Girl (Comedy, Drama, Romance, 1966)
56		Mischief (Comedy, Romance, 1985)
56		Moonrise Kingdom (Adventure, Comedy, Drama, Romance, 2012)
55		Working Girl (Comedy, Drama, Romance, 1988)
55		California Suite (Comedy, Drama, Romance, 1978)
52		Sex and Death 101 (Comedy, Drama, Romance, 2007)
52		YPF (Comedy, Drama, Romance, 2007)
52		All of Me (Comedy, Fantasy, Romance, 1984)
52		Something's Gotta Give (Comedy, Drama, Romance, 2003)
52		The Rules of Attraction (Comedy, Drama, Romance, 2002)
52		The Hotel New Hampshire (Comedy, Drama, Romance, 1984)
52		Spring Break (Comedy, Romance, 1983)
52		Lawless Heart (Comedy, Drama, Romance, 2001)
52		I Am a Sex Addict (Biography, Comedy, Romance, 2005)
52		Saving Silverman (Comedy, Crime, Romance, 2001)
52		Get Over It (Comedy, Romance, 2001)
52		The Fortune Cookie (Comedy, Romance, 1966)
52		Hall Pass (Comedy, Romance, 2011)
52		There's a Girl in My Soup (Comedy, Romance, 1970)
52		The Dictator (Comedy, Romance, 2012)
52		Sex and the Single Girl (Comedy, Romance, 1964)
52		Love & Other Drugs (Comedy, Drama, Romance, 2010)
52		Zus & zo (Comedy, Fantasy, Romance, 2001)
51		Innocent Blood (Action, Comedy, Crime, Romance, 1992)
50		Some Girls (Comedy, Drama, Romance, 1988)
50		I Wanna Hold Your Hand (Comedy, Music, Romance, 1978)
49		PK (Comedy, Drama, Romance, 2014)
49		Pretty Woman (Comedy, Romance, 1990)
48		Silver Linings Playbook (Comedy, Drama, Romance, 2012)
48		Adam's Rib (Comedy, Drama, Romance, 1949)
48		Horse Feathers (Comedy, Musical, Romance, 1932)
48		Unfaithfully Yours (Comedy, Music, Romance, 1948)
47		Sidewalks of New York (Comedy, Romance, 2001)
47		Storytelling (Comedy, Drama, Romance, 2001)
47		Friends with Benefits (Comedy, Romance, 2011)
47		The Ballad of Cable Hogue (Comedy, Drama, Romance, 1970)
47		Hysteria (Comedy, Romance, 2011)
47		Conception (Comedy, Romance, 2011)
47		New Year's Eve (Comedy, Romance, 2011)
47		Girl Fever (Comedy, Romance, 2002)
47		Wilbur Wants to Kill Himself (Comedy, Drama, Romance, 2002)
47		Hope Springs (Comedy, Drama, Romance, 2012)
47		The Girl Next Door (Comedy, Drama, Romance, 2004)
47		Les poupées russes (Comedy, Drama, Romance, 2005)
47		My Wife Is an Actress (Comedy, Drama, Romance, 2001)
47		Dr. T & the Women (Comedy, Drama, Romance, 2000)
47		I Like It Like That (Comedy, Drama, Romance, 1994)
47		Exit to Eden (Comedy, Crime, Romance, 1994)
47		So I Married an Axe Murderer (Comedy, Romance, 1993)
47		A Foreign Affair (Comedy, Drama, Romance, 1948)
47		The Bounty Hunter (Action, Comedy, Romance, 2010)
47		My Best Friend's Girl (Comedy, Romance, 2008)
47		Moscow on the Hudson (Comedy, Drama, Romance, 1984)
47		I Could Never Be Your Woman (Comedy, Drama, Romance, 2007)
47		Pushing Tin (Comedy, Drama, Romance, 1999)
47		Love Ranch (Comedy, Drama, Romance, 2010)
47		Wedding Daze (Comedy, Romance, 2006)
47		Last Night (Comedy, Drama, Romance, 1998)
46		Better Off Dead... (Comedy, Romance, 1985)
46		Girls Just Want to Have Fun (Comedy, Music, Romance, 1985)
46		Nothing in Common (Comedy, Drama, Romance, 1986)
45		Barfly (Comedy, Drama, Romance, 1987)
45		Castle Keep (Action, Comedy, Drama, Romance, 1969)
45		8 femmes (Comedy, Crime, Musical, Romance, 2002)
45		Bull Durham (Comedy, Romance, Sport, 1988)
45		Youth (Comedy, Drama, Music, Romance, 2015)
44		Creator (Comedy, Romance, Sci-Fi, 1985)
44		Caveman (Comedy, Romance, Sci-Fi, 1981)
44		The Girl Was Young (Crime, Mystery, Romance, 1937)
44		Real Genius (Comedy, Romance, Sci-Fi, 1985)
43		Frankie and Johnny (Comedy, Drama, Romance, 1991)
43		Making Mr. Right (Comedy, Romance, Sci-Fi, 1987)
42		Going the Distance (Comedy, Romance, 2010)
42		No Strings Attached (Comedy, Romance, 2011)
42		My Son the Fanatic (Comedy, Drama, Romance, 1997)
42		A New Leaf (Comedy, Romance, 1971)
42		Guess Who (Comedy, Romance, 2005)
42		The Velocity of Gary (Comedy, Drama, Romance, 1998)
42		The Kids Are All Right (Comedy, Drama, Romance, 2010)
42		Forever Lulu (Comedy, Romance, 2000)
42		Conversations with Other Women (Comedy, Drama, Romance, 2005)
42		Even Cowgirls Get the Blues (Comedy, Drama, Romance, 1993)
42		Roxie Hart (Comedy, Crime, Romance, 1942)
42		Wedding Crashers (Comedy, Romance, 2005)
42		Drop Dead Gorgeous (Comedy, Romance, Thriller, 1999)
42		Americano (Comedy, Romance, 2005)
42		This Is 40 (Comedy, Romance, 2012)
42		Venus (Comedy, Drama, Romance, 2006)
42		Now You Know (Comedy, Romance, 2002)
42		Obsluhoval jsem anglického krále (Comedy, Drama, Romance, 2006)
42		Pretty Poison (Comedy, Crime, Romance, 1968)
42		American Wedding (Comedy, Romance, 2003)
42		Tootsie (Comedy, Drama, Romance, 1982)
42		Free Enterprise (Comedy, Romance, 1998)
42		Beach Party (Comedy, Musical, Romance, 1963)
42		Buying the Cow (Comedy, Romance, 2002)
42		Pumpkin (Comedy, Drama, Romance, 2002)
42		Cashback (Comedy, Drama, Romance, 2006)
42		Love and Other Disasters (Comedy, Romance, 2006)
42		2 Days in Paris (Comedy, Drama, Romance, 2007)
42		The Other Sister (Comedy, Drama, Romance, 1999)
42		Shanghai Kiss (Comedy, Drama, Romance, 2007)
41		About Last Night... (Comedy, Drama, Romance, 1986)
41		Memoirs of an Invisible Man (Comedy, Romance, Sci-Fi, 1992)
40		Tromeo and Juliet (Action, Comedy, Drama, Romance, 1996)
40		The Nutty Professor (Comedy, Romance, Sci-Fi, 1996)
40		Desert Heat (Action, Comedy, Drama, Romance, 1999)
40		Multiplicity (Comedy, Romance, Sci-Fi, 1996)
40		Bride of Chucky (Comedy, Fantasy, Horror, Romance, 1998)
40		Junior (Comedy, Romance, Sci-Fi, 1994)
40		My Super Ex-Girlfriend (Comedy, Romance, Sci-Fi, 2006)
40		Love at First Bite (Comedy, Romance, 1979)
40		The Mouse on the Moon (Comedy, Romance, Sci-Fi, 1963)
40		Roxanne (Comedy, Romance, 1987)
40		The Nutty Professor (Comedy, Romance, Sci-Fi, 1963)
40		The Invisible Woman (Comedy, Romance, Sci-Fi, 1940)
40		Paint Your Wagon (Comedy, Drama, Musical, Romance, 1969)
40		Romancing the Stone (Action, Adventure, Comedy, Romance, 1984)
40		Can't Buy Me Love (Comedy, Drama, Romance, 1987)
40		Summer School (Comedy, Romance, 1987)
40		For Keeps? (Comedy, Drama, Romance, 1988)
40		Nutty Professor II: The Klumps (Comedy, Romance, Sci-Fi, 2000)
39		The Goodbye Girl (Comedy, Drama, Romance, 1977)
39		Remo Williams: The Adventure Begins (Action, Adventure, Comedy, Romance, 1985)
39		Cousins (Comedy, Romance, 1989)
38		HouseSitter (Comedy, Romance, 1992)
38		Father of the Bride (Comedy, Family, Romance, 1991)
38		Leap of Faith (Comedy, Drama, Romance, 1992)
38		Hello Again (Comedy, Drama, Fantasy, Romance, 1987)
38		Doc Hollywood (Comedy, Drama, Romance, 1991)
38		Saving Face (Comedy, Drama, Romance, 2004)
38		The Talk of the Town (Comedy, Drama, Romance, 1942)
37		Secretary (Comedy, Drama, Romance, 2002)
37		Finding Bliss (Comedy, Romance, 2009)
37		Tokyo Fiancée (Comedy, Drama, Romance, 2014)
37		Take Me Home Tonight (Comedy, Drama, Romance, 2011)
37		Grumpy Old Men (Comedy, Drama, Romance, 1993)
37		Middle of Nowhere (Comedy, Drama, Romance, 2008)
37		The Singles Ward (Comedy, Drama, Romance, 2002)
37		The Goddess of 1967 (Comedy, Drama, Romance, 2000)
37		Liberal Arts (Comedy, Drama, Romance, 2012)
37		While You Were Sleeping (Comedy, Drama, Romance, 1995)
37		Away We Go (Comedy, Drama, Romance, 2009)
37		Moonlight and Valentino (Comedy, Drama, Romance, 1995)
37		Adam and Eve (Comedy, Drama, Romance, 2005)
37		Did You Hear About the Morgans? (Comedy, Drama, Romance, 2009)
37		It's Complicated (Comedy, Drama, Romance, 2009)
37		Italiensk for begyndere (Comedy, Drama, Romance, 2000)
37		World Without End (Adventure, Romance, Sci-Fi, 1956)
37		Life as We Know It (Comedy, Drama, Romance, 2010)
37		Nico and Dani (Comedy, Drama, Romance, 2000)
37		Carry on Nurse (Comedy, Romance, 1959)
37		I Love You, Beth Cooper (Comedy, Romance, 2009)
37		The Invention of Lying (Comedy, Fantasy, Romance, 2009)
37		Summer of '42 (Comedy, Drama, Romance, 1971)
37		Christmas in Connecticut (Comedy, Romance, 1945)
37		Kings & Queen (Comedy, Drama, Romance, 2004)
37		Mighty Aphrodite (Comedy, Fantasy, Romance, 1995)
37		Father of the Bride Part II (Comedy, Family, Romance, 1995)
37		Numb (Comedy, Drama, Romance, 2007)
37		Good Luck Chuck (Comedy, Romance, 2007)
37		The Disorderly Orderly (Comedy, Romance, 1964)
37		Undertaking Betty (Comedy, Romance, 2002)
37		The Other Woman (Comedy, Romance, 2014)
37		Suburban Girl (Comedy, Drama, Romance, 2007)
37		A Night at the Roxbury (Comedy, Music, Romance, 1998)
37		That Awkward Moment (Comedy, Romance, 2014)
37		Better Than Chocolate (Comedy, Drama, Romance, 1999)
37		Stairway to Heaven (Comedy, Drama, Fantasy, Romance, 1946)
37		Anything Else (Comedy, Romance, 2003)
37		La vérité si je mens! (Comedy, Romance, 1997)
37		You Will Meet a Tall Dark Stranger (Comedy, Drama, Romance, 2010)
37		Seres queridos (Comedy, Romance, 2004)
37		Welcome to Mooseport (Comedy, Romance, 2004)
37		Avenue Montaigne (Comedy, Drama, Romance, 2006)
37		What's Cooking? (Comedy, Drama, Romance, 2000)
37		Confetti (Comedy, Music, Romance, 2006)
37		Silver Streak (Action, Comedy, Crime, Romance, 1976)
37		Jerry Maguire (Comedy, Drama, Romance, 1996)
37		The Mirror Has Two Faces (Comedy, Drama, Romance, 1996)
37		That Old Feeling (Comedy, Romance, 1997)
36		Fatso (Comedy, Drama, Romance, 1980)
36		About Time (Comedy, Drama, Fantasy, Romance, 2013)
36		The Barbarian Invasions (Comedy, Crime, Drama, Romance, 2003)
36		Legal Eagles (Comedy, Crime, Romance, 1986)

Notes: Movies similar to The Man with Two Brains, Movies like The Man with Two Brains, Comedy, Romance, Sci-Fi, Carl Reiner, Steve Martin, Kathleen Turner, David Warner, Paul Benedict, Films, Video, Movie Similarities