45		Manhattan Murder Mystery (Comedy, Mystery, 1993)
40		Hail, Caesar! (Comedy, Mystery, 2016)
40		The Hangover Part II (Comedy, Mystery, 2011)
40		The Overnight (Comedy, Mystery, 2015)
39		Clue (Comedy, Crime, Mystery, 1985)
39		Kindergarten Cop (Comedy, 1990)
38		Hot Fuzz (Action, Comedy, Mystery, 2007)
38		Kiss Kiss Bang Bang (Comedy, Crime, Mystery, 2005)
36		Short Cuts (Comedy, Drama, 1993)
36		Fletch Lives (Comedy, Mystery, Crime, 1989)
34		The Big Lebowski (Comedy, Crime, 1998)
34		The Freshman (Comedy, Crime, 1990)
34		Nine Months (Comedy, Romance, 1995)
34		See No Evil, Hear No Evil (Comedy, Crime, 1989)
33		The Curse of the Jade Scorpion (Comedy, Crime, Mystery, 2001)
33		Weekend at Bernie's (Adventure, Comedy, Crime, 1989)
33		Gosford Park (Comedy, Drama, Mystery, 2001)
32		An Ideal Husband (Comedy, Romance, 1999)
32		Six Degrees of Separation (Comedy, Drama, Mystery, 1993)
32		Cookie's Fortune (Comedy, Drama, 1999)
32		The Opposite of Sex (Comedy, 1998)
32		Flypaper (Comedy, Crime, Mystery, 2011)
32		Dead Men Don't Wear Plaid (Comedy, Crime, Mystery, 1982)
32		Money Talks (Action, Comedy, Crime, 1997)
32		The People Under the Stairs (Comedy, Horror, Mystery, 1991)
31		Evolution (Comedy, Sci-Fi, 2001)
31		The 'Burbs (Comedy, Mystery, Thriller, 1989)
31		Terminal Velocity (Action, Comedy, Mystery, 1994)
31		The Whole Nine Yards (Comedy, Crime, 2000)
31		Who's Harry Crumb? (Comedy, Crime, Mystery, 1989)
30		Starsky & Hutch (Comedy, Crime, 2004)
30		Laws of Attraction (Comedy, Romance, 2004)
30		Suicide Kings (Comedy, Drama, Mystery, 1997)
30		Irrational Man (Comedy, Drama, 2015)
30		My Cousin Vinny (Comedy, Crime, 1992)
30		Calvary (Comedy, Drama, 2014)
30		Cocoon: The Return (Adventure, Comedy, Mystery, 1988)
30		So I Married an Axe Murderer (Comedy, Romance, 1993)
30		Maps to the Stars (Comedy, Drama, 2014)
30		Crimes and Misdemeanors (Comedy, Drama, 1989)
30		Oscar (Comedy, Crime, 1991)
29		Cadillac Man (Comedy, Crime, 1990)
29		Benny & Joon (Comedy, Drama, Romance, 1993)
29		I Love You to Death (Comedy, Crime, 1990)
29		The Dream Team (Comedy, 1989)
29		Sister Act (Comedy, Crime, Music, 1992)
29		Heart and Souls (Comedy, Drama, Fantasy, 1993)
29		Fletch (Comedy, Crime, Mystery, 1985)
28		Pump Up the Volume (Comedy, Drama, Music, 1990)
28		Snatch (Comedy, Crime, 2000)
28		Dude, Where's My Car? (Comedy, Mystery, Sci-Fi, 2000)
28		To Die For (Comedy, Crime, Drama, 1995)
28		Beverly Hills Ninja (Action, Comedy, 1997)
28		Drowning Mona (Crime, Mystery, Comedy, 2000)
28		Men at Work (Action, Comedy, Crime, 1990)
28		Super Troopers (Comedy, Crime, Mystery, 2001)
28		Human Nature (Comedy, Drama, Mystery, 2001)
28		The Last Supper (Comedy, Crime, Drama, 1995)
28		Head Over Heels (Comedy, Mystery, Romance, 2001)
28		Turner & Hooch (Comedy, Crime, Drama, 1989)
28		Empire Records (Comedy, Drama, Music, 1995)
28		Midnight Run (Action, Comedy, Crime, 1988)
27		Analyze This (Comedy, Crime, 1999)
27		Married to the Mob (Comedy, Crime, Romance, 1988)
27		Heathers (Comedy, Crime, Drama, 1988)
27		Broken Flowers (Comedy, Drama, Mystery, 2005)
27		Kaboom (Comedy, Mystery, Romance, 2010)
27		Housebound (Comedy, Horror, Mystery, 2014)
27		Mortdecai (Action, Comedy, Mystery, 2015)
27		Forrest Gump (Comedy, Drama, 1994)
27		Assassination of a High School President (Comedy, Crime, Mystery, 2008)
27		Shrooms (Comedy, Horror, Mystery, 2007)
27		Without a Paddle (Adventure, Comedy, Mystery, 2004)
27		Southland Tales (Comedy, Mystery, Sci-Fi, 2006)
27		Bubba Ho-Tep (Comedy, Fantasy, Mystery, 2002)
27		Scoop (Comedy, Crime, Mystery, 2006)
27		Ruthless People (Comedy, Crime, 1986)
26		Night on Earth (Comedy, Drama, 1991)
26		The Station Agent (Comedy, Drama, 2003)
26		Dazed and Confused (Comedy, 1993)
26		Police Academy (Comedy, 1984)
26		Barton Fink (Comedy, Drama, 1991)
26		Prizzi's Honor (Comedy, Crime, Drama, 1985)
26		Naked (Comedy, Drama, 1993)
25		Soapdish (Comedy, Romance, 1991)
25		King Ralph (Comedy, Romance, 1991)
25		Nothing But Trouble (Comedy, 1991)
25		Slacker (Comedy, Drama, 1991)
25		City Slickers (Comedy, 1991)
25		Hot Shots! (Action, Comedy, 1991)
25		What About Bob? (Comedy, 1991)
25		Don't Tell Mom the Babysitter's Dead (Comedy, 1991)
25		Problem Child 2 (Comedy, Family, 1991)
25		The Naked Gun 2½: The Smell of Fear (Comedy, Crime, 1991)
25		Captain Ron (Adventure, Comedy, 1992)
25		Coneheads (Comedy, Sci-Fi, 1993)
25		Weekend at Bernie's II (Comedy, Fantasy, 1993)
25		Dennis the Menace (Comedy, Family, 1993)
25		Made in America (Comedy, 1993)
25		Clerks (Comedy, 1994)
25		The Beverly Hillbillies (Comedy, Family, 1993)
25		Wayne's World 2 (Comedy, Music, 1993)
25		Sister Act 2: Back in the Habit (Comedy, Music, 1993)
25		Addams Family Values (Comedy, Fantasy, 1993)
25		Hot Shots! Part Deux (Action, Comedy, 1993)
25		Dave (Comedy, Romance, 1993)
25		Encino Man (Comedy, 1992)
25		The Player (Comedy, Crime, Drama, 1992)
25		Wayne's World (Comedy, Music, 1992)
25		Shadows and Fog (Comedy, 1991)
25		HouseSitter (Comedy, Romance, 1992)
25		Braindead (Comedy, Fantasy, Horror, 1992)
25		The Distinguished Gentleman (Comedy, Crime, 1992)
25		Rosencrantz & Guildenstern Are Dead (Comedy, Drama, 1990)
25		Bob Roberts (Comedy, 1992)
25		The Addams Family (Comedy, Fantasy, 1991)
25		Dead Poets Society (Comedy, Drama, 1989)
25		God Bless America (Comedy, Crime, 2011)
25		The Onion Movie (Comedy, 2008)
25		Where the Heart Is (Comedy, Drama, Romance, 2000)
25		National Lampoon's Christmas Vacation (Comedy, Family, 1989)
25		Barbershop (Comedy, Drama, 2002)
25		Beverly Hills Cop (Action, Comedy, Crime, 1984)
25		Horrible Bosses (Comedy, Crime, 2011)
25		Do the Right Thing (Comedy, Drama, 1989)
25		The Interview (Comedy, 2014)
25		Keanu (Action, Comedy, 2016)
25		Living in Oblivion (Comedy, Drama, 1995)
25		Chopper (Biography, Comedy, Crime, 2000)
25		A Hologram for the King (Comedy, Drama, 2016)
25		Te wu mi cheng (Action, Comedy, Crime, 2001)
25		The Banger Sisters (Comedy, Drama, 2002)
24		The Kids Are All Right (Comedy, Drama, Romance, 2010)
24		Shanghai Knights (Action, Adventure, Comedy, 2003)
24		Torque (Action, Comedy, Crime, 2004)
24		National Treasure: Book of Secrets (Action, Adventure, Comedy, 2007)
24		Pineapple Express (Action, Comedy, Crime, 2008)
24		30 Minutes or Less (Action, Comedy, Crime, 2011)
24		City Slickers II: The Legend of Curly's Gold (Comedy, Western, 1994)
24		Renaissance Man (Comedy, Drama, 1994)
24		With Honors (Comedy, Drama, 1994)
24		PCU (Comedy, 1994)
24		Bullets Over Broadway (Comedy, Crime, 1994)
24		Kill Me Three Times (Action, Comedy, Thriller, 2014)
24		Big Mommas: Like Father, Like Son (Action, Comedy, Crime, 2011)
24		Crazy, Stupid, Love. (Comedy, Drama, Romance, 2011)
24		Robot & Frank (Comedy, Crime, Drama, 2012)
24		Don Jon (Comedy, Drama, Romance, 2013)
24		Wild Target (Action, Comedy, Crime, 2010)
24		Only You (Comedy, Romance, 1994)
24		The Englishman Who Went Up a Hill But Came Down a Mountain (Comedy, Drama, 1995)
24		Friday (Comedy, Drama, 1995)
24		Canadian Bacon (Comedy, 1995)
24		Clueless (Comedy, Romance, 1995)
24		To Wong Foo Thanks for Everything, Julie Newmar (Comedy, Drama, 1995)
24		Tommy Boy (Adventure, Comedy, 1995)
24		The Brady Bunch Movie (Comedy, 1995)
24		I.Q. (Comedy, Romance, 1994)
24		Ready to Wear (Comedy, Drama, 1994)
24		Rumble in the Bronx (Action, Comedy, 1995)
24		Billy Madison (Comedy, 1995)
24		Smoke (Comedy, Drama, 1995)
24		Welcome to the Dollhouse (Comedy, Drama, 1995)
24		Four Rooms (Comedy, 1995)
24		Lock, Stock and Two Smoking Barrels (Comedy, Crime, 1998)
24		The Castle (Comedy, Drama, 1997)
24		Dumb & Dumber (Comedy, 1994)
24		Nobody's Fool (Comedy, Drama, 1994)
24		8 femmes (Comedy, Crime, Musical, 2002)
24		Waiting for Guffman (Comedy, 1996)
24		Grumpier Old Men (Comedy, Romance, 1995)
24		Mallrats (Comedy, Romance, 1995)
24		Ace Ventura: When Nature Calls (Adventure, Comedy, 1995)
24		Major League II (Comedy, Sport, 1994)
24		Ri¢hie Ri¢h (Comedy, Family, 1994)
24		Swimming with Sharks (Comedy, Crime, 1994)
24		Sabrina (Comedy, Drama, 1995)
24		She-Devil (Comedy, 1989)
24		The War of the Roses (Comedy, Romance, 1989)
24		Look Who's Talking (Comedy, Romance, 1989)
24		We're No Angels (Comedy, Crime, 1989)
24		Joe Versus the Volcano (Comedy, Romance, 1990)
24		Planes, Trains & Automobiles (Comedy, Drama, 1987)
24		Bird on a Wire (Action, Comedy, 1990)
24		Pretty Woman (Comedy, Romance, 1990)
24		Uncle Buck (Comedy, 1989)
24		The Gods Must Be Crazy II (Comedy, 1989)
24		Police Academy 6: City Under Siege (Comedy, Crime, 1989)
24		A Fish Called Wanda (Comedy, Crime, 1988)
24		The Naked Gun: From the Files of Police Squad! (Comedy, Crime, 1988)
24		Radio Days (Comedy, 1987)
24		Withnail & I (Comedy, Drama, 1987)
24		UHF (Comedy, Drama, 1989)
24		Major League (Comedy, Sport, 1989)
24		Quick Change (Comedy, Crime, 1990)
24		Parenthood (Comedy, Drama, 1989)
24		Ace Ventura: Pet Detective (Comedy, 1994)
24		Sneakers (Comedy, Crime, Drama, 1992)
24		The Paper (Comedy, Drama, 1994)
24		Problem Child (Comedy, Family, 1990)
24		Loaded Weapon 1 (Action, Comedy, Crime, 1993)
24		Naked Gun 33 1/3: The Final Insult (Comedy, Crime, 1994)
24		The Hudsucker Proxy (Comedy, Fantasy, 1994)
24		The Adventures of Priscilla, Queen of the Desert (Comedy, Music, 1994)
24		Stop! Or My Mom Will Shoot (Action, Comedy, Family, 1992)
24		Death Becomes Her (Comedy, Fantasy, Horror, 1992)
24		Greedy (Comedy, 1994)
24		Air America (Action, Comedy, 1990)
24		Guarding Tess (Comedy, Drama, 1994)
24		My Blue Heaven (Comedy, Crime, 1990)
24		Home Alone (Comedy, Family, 1990)
24		Postcards from the Edge (Comedy, Drama, 1990)

Notes: Movies similar to The Gun in Betty Lou's Handbag, Movies like The Gun in Betty Lou's Handbag, Comedy, Mystery, Allan Moyle, Penelope Ann Miller, Eric Thal, Alfre Woodard, Julianne Moore, Films, Video, Movie Similarities