55		Sleeper (Comedy, Sci-Fi, 1973)
50		Evolution (Comedy, Sci-Fi, 2001)
47		Idiocracy (Adventure, Comedy, Sci-Fi, 2006)
46		The Incredible Shrinking Woman (Comedy, Sci-Fi, 1981)
46		Simon (Comedy, Sci-Fi, 1980)
45		Mystery Science Theater 3000: The Movie (Comedy, Sci-Fi, 1996)
45		Her Husband's Affairs (Comedy, Sci-Fi, 1947)
45		The Road to Hong Kong (Comedy, Sci-Fi, 1962)
45		Repli-Kate (Comedy, Sci-Fi, 2002)
45		Coneheads (Comedy, Sci-Fi, 1993)
45		Absolutely Anything (Comedy, Sci-Fi, 2015)
45		Freaked (Comedy, Sci-Fi, 1993)
45		Inspector Gadget (Action, Adventure, Comedy, Sci-Fi, 1999)
44		Henry's Night In (Comedy, Sci-Fi, 1969)
44		Crimes of the Future (Comedy, Sci-Fi, 1970)
44		2069 A.D. (Comedy, Sci-Fi, 1969)
44		Dr. Dildo's Secret (Comedy, Sci-Fi, 1970)
44		Hello Down There (Comedy, Sci-Fi, 1969)
44		The Bed Sitting Room (Comedy, Sci-Fi, 1969)
44		The Monitors (Comedy, Sci-Fi, 1969)
44		Dark Star (Comedy, Sci-Fi, 1974)
44		Flesh Gordon (Comedy, Sci-Fi, 1974)
44		The Sexplorer (Comedy, Sci-Fi, 1975)
43		The Day the Fish Came Out (Comedy, Sci-Fi, 1967)
43		2076 Olympiad (Comedy, Sci-Fi, 1977)
42		Way... Way Out (Comedy, Sci-Fi, 1966)
42		Dr. Goldfoot and the Bikini Machine (Comedy, Sci-Fi, 1965)
42		Night of the Creeps (Comedy, Horror, Sci-Fi, 1986)
42		Spaced Out (Comedy, Sci-Fi, 1979)
42		Very Close Encounters of the Fourth Kind (Comedy, Sci-Fi, 1978)
42		Dr. Plonk (Action, Comedy, Sci-Fi, 2007)
42		Re-Animator (Comedy, Horror, Sci-Fi, 1985)
42		Repo Man (Comedy, Crime, Sci-Fi, 1984)
41		Caveman (Comedy, Sci-Fi, 1981)
41		Kiss Me Quick! (Comedy, Sci-Fi, 1964)
41		50,000 B.C. (Before Clothing) (Comedy, Sci-Fi, 1963)
41		Heartbeeps (Sci-Fi, Comedy, 1981)
40		The Roly Poly Man (Comedy, Sci-Fi, 1994)
40		U.F.O. (Comedy, Sci-Fi, 1993)
40		Space Case (Comedy, Sci-Fi, 1992)
40		The Revenge of the Teenage Vixens from Outer Space (Comedy, Sci-Fi, 1985)
40		Tribulation 99: Alien Anomalies Under America (Comedy, Sci-Fi, 1992)
40		UFOria (Comedy, Sci-Fi, 1985)
40		Walkin' on Sunshine: The Movie (Comedy, Sci-Fi, 1997)
40		Hyperspace (Sci-Fi, Comedy, 1984)
40		Battle for the Planet of the Apes (Action, Sci-Fi, 1973)
40		Orgazmo (Comedy, Sci-Fi, 1997)
40		Morons from Outer Space (Comedy, Sci-Fi, 1985)
40		Plan 10 from Outer Space (Comedy, Sci-Fi, 1995)
40		Hell's Belles (Comedy, Sci-Fi, 1995)
40		Niagaravation (Comedy, Sci-Fi, 1995)
40		Invasion: Stanford 1991 A.D. (Comedy, Sci-Fi, 1990)
40		Meet the Applegates (Comedy, Sci-Fi, 1990)
40		As Time Goes by (Comedy, Sci-Fi, 1988)
40		I Was a Zombie for the F.B.I. (Comedy, Sci-Fi, 1982)
40		Norman's Awesome Experience (Comedy, Sci-Fi, 1988)
40		The Invisible Kid (Comedy, Sci-Fi, 1988)
40		Illegal Alien (Comedy, Sci-Fi, 1982)
40		Eat and Run (Comedy, Sci-Fi, 1987)
40		Xing ji dun tai (Sci-Fi, Comedy, 1983)
40		Amazon Women on the Moon (Comedy, Sci-Fi, 1987)
40		What's Up, Hideous Sun Demon (Comedy, Sci-Fi, 1983)
40		The American Way (Comedy, Sci-Fi, 1986)
40		Terminal City Ricochet (Comedy, Sci-Fi, 1990)
40		The Spirit of '76 (Comedy, Sci-Fi, 1990)
40		Britannia Hospital (Comedy, Sci-Fi, 1982)
40		Wooly Booly: Ang classmate kong alien (Comedy, Sci-Fi, 1989)
40		The Brother from Another Planet (Comedy, Sci-Fi, 1984)
40		It Came from Somewhere Else (Comedy, Sci-Fi, 1988)
40		Airplane II: The Sequel (Comedy, Sci-Fi, 1982)
40		Mutant on the Bounty (Comedy, Sci-Fi, 1989)
40		The Trouble with Dick (Comedy, Sci-Fi, 1986)
40		Virtue (Comedy, Sci-Fi, 1999)
40		Child's Play (Comedy, Sci-Fi, 1954)
40		The Atomic Kid (Comedy, Sci-Fi, 1954)
40		Robodoc (Comedy, Sci-Fi, 2009)
40		The Killer Robots and the Battle for the Cosmic Potato (Comedy, Sci-Fi, 2009)
40		Hot Tub Time Machine (Comedy, Sci-Fi, 2010)
40		The Twonky (Comedy, Sci-Fi, 1953)
40		Final Flesh (Comedy, Sci-Fi, 2009)
40		The Noble Experiment (Comedy, Sci-Fi, 1955)
40		Frequently Asked Questions About Time Travel (Comedy, Sci-Fi, 2009)
40		Hank, Aaron and the Alien from Outer Space (Comedy, Sci-Fi, 2009)
40		Visit to a Small Planet (Comedy, Sci-Fi, 1960)
40		The 30 Foot Bride of Candy Rock (Comedy, Sci-Fi, 1959)
40		Totò nella luna (Comedy, Sci-Fi, 1958)
40		The Mating Habits of the Earthbound Human (Comedy, Sci-Fi, 1999)
40		When London Sleeps It Came Alive (Comedy, Sci-Fi, 2010)
40		Night of the Alien (Comedy, Sci-Fi, 2011)
40		Revenge of the Bimbot Zombie Killers (Comedy, Sci-Fi, 2014)
40		Time Flies (Comedy, Sci-Fi, 1944)
40		Hot Tub Time Machine 2 (Comedy, Sci-Fi, 2015)
40		End of Days, Inc. (Comedy, Sci-Fi, 2015)
40		Probable Robot (Comedy, Sci-Fi, 2015)
40		Atop the Fourth Wall: The Movie (Comedy, Sci-Fi, 2015)
40		The Search for Simon (Comedy, Sci-Fi, 2013)
40		Serena the Sexplorer (Comedy, Sci-Fi, 2013)
40		Folklore (Comedy, Sci-Fi, 2012)
40		Transolar Galactica (Comedy, Sci-Fi, 2011)
40		Rock Jocks (Comedy, Sci-Fi, 2012)
40		Mister Drake's Duck (Sci-Fi, Comedy, 1951)
40		Space Milkshake (Comedy, Sci-Fi, 2012)
40		The Perfect Woman (Comedy, Sci-Fi, 1949)
40		Horror in the Wind (Comedy, Sci-Fi, 2008)
40		Have Rocket -- Will Travel (Comedy, Sci-Fi, 1959)
40		Cyxork 7 (Comedy, Sci-Fi, 2006)
40		Alien Autopsy (Comedy, Sci-Fi, 2006)
40		From Other Worlds (Comedy, Sci-Fi, 2004)
40		I epithesi tou gigantiaiou mousaka (Comedy, Sci-Fi, 1999)
40		The Last Dudes on Earth (Comedy, Sci-Fi, 2005)
40		Phil the Alien (Comedy, Sci-Fi, 2004)
40		Gargaroth (Comedy, Sci-Fi, 2004)
40		Evil Alien Conquerors (Comedy, Sci-Fi, 2003)
40		Godzilla 2001 (Comedy, Sci-Fi, 2001)
40		Alien Sex Party (Comedy, Sci-Fi, 2003)
40		Target Audience 9.1 (Comedy, Sci-Fi, 2007)
40		What Planet Are You From? (Comedy, Sci-Fi, 2000)
40		Mock Up on Mu (Comedy, Sci-Fi, 2008)
40		The Three Stooges in Orbit (Comedy, Sci-Fi, 1962)
40		The Animal (Comedy, Sci-Fi, 2001)
40		Uchuujin from Outer Space (Comedy, Sci-Fi, 2007)
40		Superstarlet A.D. (Comedy, Sci-Fi, 2000)
40		I'll Believe You (Comedy, Sci-Fi, 2006)
39		Piranha (Comedy, Horror, Sci-Fi, 1978)
38		The Invisible Man (Comedy, Horror, Sci-Fi, 1933)
37		It Happens Every Spring (Comedy, Sci-Fi, Sport, 1949)
37		Man's Best Friend (Comedy, Horror, Sci-Fi, 1993)
37		The Borrower (Comedy, Horror, Sci-Fi, 1991)
37		Monster in the Closet (Comedy, Horror, Sci-Fi, 1986)
37		Alien Trespass (Comedy, Horror, Sci-Fi, 2009)
37		Chopping Mall (Comedy, Horror, Sci-Fi, 1986)
37		Schlock (Comedy, Horror, Sci-Fi, 1973)
35		Doctor X (Comedy, Crime, Horror, Sci-Fi, 1932)
35		Beyond Re-Animator (Comedy, Crime, Horror, Sci-Fi, 2003)
34		The Cat from Outer Space (Comedy, Family, Sci-Fi, 1978)
34		Back to the Future (Adventure, Comedy, Sci-Fi, 1985)
33		The Misadventures of Merlin Jones (Family, Comedy, Sci-Fi, 1964)
33		The Flesh Eaters (Comedy, Horror, Sci-Fi, 1964)
33		Son of Flubber (Comedy, Sci-Fi, Family, 1963)
32		Bicentennial Man (Comedy, Drama, Sci-Fi, 1999)
32		Top of the Food Chain (Comedy, Horror, Sci-Fi, 1999)
32		Nothing Lasts Forever (Comedy, Fantasy, Sci-Fi, 1984)
32		There's Nothing Out There (Comedy, Horror, Sci-Fi, 1991)
32		Doctor S Battles the Sex Crazed Reefer Zombies: The Movie (Comedy, Horror, Sci-Fi, 2009)
32		Creator (Comedy, Romance, Sci-Fi, 1985)
32		Night of the Comet (Comedy, Horror, Sci-Fi, 1984)
32		Body Melt (Horror, Comedy, Sci-Fi, 1993)
32		Humanoids from Atlantis (Action, Comedy, Sci-Fi, 1992)
32		Mars Attacks! (Action, Comedy, Sci-Fi, 1996)
32		The Return of Swamp Thing (Sci-Fi, Horror, Comedy, 1989)
32		Now You See Him, Now You Don't (Family, Comedy, Sci-Fi, 1972)
32		Invasion of the Saucer Men (Comedy, Horror, Sci-Fi, 1957)
32		Cyborg 2087 (Sci-Fi, 1966)
32		Beware! The Blob (Comedy, Horror, Sci-Fi, 1972)
32		The Million Dollar Duck (Comedy, Family, Sci-Fi, 1971)
32		Slaughterhouse-Five (Comedy, Drama, Sci-Fi, 1972)
32		The Bowery Boys Meet the Monsters (Horror, Comedy, Sci-Fi, 1954)
32		The Absent Minded Professor (Comedy, Family, Sci-Fi, 1961)
32		Ha-Trempist (Action, Comedy, Sci-Fi, 1972)
31		Bride of Frankenstein (Comedy, Drama, Horror, Sci-Fi, 1935)
31		Toomorrow (Comedy, Musical, Sci-Fi, 1970)
31		Mad Max (Action, Adventure, Sci-Fi, 1979)
31		The Love Factor (Comedy, Fantasy, Sci-Fi, 1969)
31		Escape from New York (Action, Sci-Fi, 1981)
31		Hibernatus (Comedy, Fantasy, Sci-Fi, 1969)
31		Death Race 2000 (Action, Comedy, Sci-Fi, 1975)
31		A Boy and His Dog (Comedy, Drama, Sci-Fi, 1975)
30		Trancers (Action, Sci-Fi, 1984)
30		The Omega Man (Action, Sci-Fi, 1971)
30		Born in Flames (Comedy, Drama, Fantasy, Sci-Fi, 1983)
30		The President's Analyst (Comedy, Sci-Fi, Thriller, 1967)
30		Lilo & Stitch (Animation, Adventure, Comedy, Sci-Fi, 2002)
30		Superman (Sci-Fi, 1948)
30		Gildersleeve's Ghost (Comedy, Fantasy, Horror, Sci-Fi, 1944)
30		The Mad Doctor of Market Street (Comedy, Drama, Horror, Sci-Fi, 1942)
30		The Reluctant Astronaut (Comedy, Family, Sci-Fi, 1967)
30		Who Am I? (Action, Adventure, Comedy, Sci-Fi, 1998)
30		Matchless (Comedy, Sci-Fi, Thriller, 1967)
30		The Ambushers (Action, Comedy, Sci-Fi, 1967)
30		Spider Baby or, The Maddest Story Ever Told (Comedy, Horror, Sci-Fi, 1967)
29		RoboCop (Action, Crime, Sci-Fi, 2014)
29		Rocky Horror Show Live (Comedy, Musical, Sci-Fi, 2015)
29		The Monkey's Uncle (Family, Comedy, Sci-Fi, 1965)
29		RoboCop 2 (Action, Crime, Sci-Fi, 1990)
29		Runaway (Action, Crime, Sci-Fi, 1984)
29		Captain Celluloid vs. the Film Pirates (Sci-Fi, Action, Comedy, 1966)
29		Space Is the Place (Sci-Fi, Music, 1974)
29		The Truman Show (Comedy, Drama, Sci-Fi, 1998)
29		Hu-Man (Sci-Fi, 1975)
29		C.H.O.M.P.S. (Comedy, Family, Sci-Fi, 1979)
29		The Troops & Aliens (Comedy, Crime, Sci-Fi, 1979)
29		Where's Willie? (Comedy, Family, Sci-Fi, 1978)
28		The Mouse on the Moon (Comedy, Romance, Sci-Fi, 1963)
28		The Nutty Professor (Comedy, Romance, Sci-Fi, 1963)
28		Earthbound (Family, Sci-Fi, Comedy, 1981)
28		Buck Rogers (Romance, Sci-Fi, 1977)
28		Back to the Future Part II (Adventure, Comedy, Sci-Fi, 1989)
28		Blood Beach (Comedy, Horror, Sci-Fi, 1980)
28		Cheech and Chong's Next Movie (Comedy, Crime, Sci-Fi, 1980)
28		G.O.R.A. (Adventure, Comedy, Sci-Fi, 2004)
28		Flytrap (Comedy, Drama, Sci-Fi, 2015)
28		Modern Problems (Comedy, Fantasy, Sci-Fi, 1981)
28		The Garden's Keeper (Action, Comedy, Sci-Fi, 2015)
28		Le grand tout (Comedy, Drama, Sci-Fi, 2016)
28		Abby Sen (Comedy, Drama, Sci-Fi, 2015)
28		Things to Come (Sci-Fi, 1976)

Notes: Movies similar to The Thing with Two Heads, Movies like The Thing with Two Heads, Comedy, Sci-Fi, Lee Frost, Roosevelt Grier, Ray Milland, Don Marshall, Roger Perry, SF, Science Fiction, SciFi, Sci Fi, Films, Video, Movie Similarities