91		Zapped! (Comedy, Fantasy, Sci-Fi, 1982)
74		The Man with Two Brains (Comedy, Romance, Sci-Fi, 1983)
72		Chopping Mall (Comedy, Horror, Sci-Fi, 1986)
67		Class of Nuke 'Em High (Comedy, Horror, Sci-Fi, 1986)
65		Real Genius (Comedy, Romance, Sci-Fi, 1985)
65		The Nutty Professor (Comedy, Romance, Sci-Fi, 1963)
62		A Boy and His Dog (Comedy, Drama, Sci-Fi, 1975)
62		The Return of the Living Dead (Comedy, Horror, Sci-Fi, 1985)
60		Small Soldiers (Action, Adventure, Comedy, Sci-Fi, 1998)
58		Bill & Ted's Excellent Adventure (Adventure, Comedy, Music, Sci-Fi, 1989)
57		Re-Animator (Comedy, Horror, Sci-Fi, 1985)
56		Back to the Future Part II (Adventure, Comedy, Sci-Fi, 1989)
55		Pixels (Animation, Action, Comedy, Sci-Fi, 2015)
53		Brainscan (Comedy, Horror, Sci-Fi, 1994)
52		Nothing Lasts Forever (Comedy, Fantasy, Sci-Fi, 1984)
52		Nu ji xie ren (Action, Comedy, Crime, Sci-Fi, 1991)
48		Coneheads (Comedy, Sci-Fi, 1993)
47		Serena the Sexplorer (Comedy, Sci-Fi, 2013)
47		Night of the Creeps (Comedy, Horror, Sci-Fi, 1986)
47		Attack the Block (Action, Comedy, Sci-Fi, 2011)
46		Airplane II: The Sequel (Comedy, Sci-Fi, 1982)
46		Superman III (Action, Comedy, Sci-Fi, 1983)
45		Creator (Comedy, Romance, Sci-Fi, 1985)
45		Poultrygeist: Night of the Chicken Dead (Comedy, Horror, Musical, Sci-Fi, 2006)
45		Frankenhooker (Comedy, Horror, Sci-Fi, 1990)
45		My Science Project (Action, Adventure, Comedy, Sci-Fi, 1985)
44		My Stepmother Is an Alien (Comedy, Romance, Sci-Fi, 1988)
44		Remote Control (Comedy, Romance, Sci-Fi, 1988)
44		Nice Girls Don't Explode (Comedy, Romance, Sci-Fi, 1987)
44		Making Mr. Right (Comedy, Romance, Sci-Fi, 1987)
43		Kamillions (Comedy, Romance, Sci-Fi, 1990)
42		Space Milkshake (Comedy, Sci-Fi, 2012)
42		John Dies at the End (Comedy, Horror, Sci-Fi, 2012)
42		ZMD: Zombies of Mass Destruction (Comedy, Horror, Sci-Fi, 2009)
42		Memoirs of an Invisible Man (Comedy, Romance, Sci-Fi, 1992)
42		Bill & Ted's Bogus Journey (Adventure, Comedy, Fantasy, Sci-Fi, 1991)
42		Two Lost Worlds (Adventure, Romance, Sci-Fi, 1951)
42		Evil Aliens (Comedy, Horror, Sci-Fi, 2005)
41		Junior (Comedy, Romance, Sci-Fi, 1994)
40		The Nutty Professor (Comedy, Romance, Sci-Fi, 1996)
40		Underworld: Evolution (Action, Adventure, Fantasy, Sci-Fi, 2006)
40		Pajama Party (Comedy, Musical, Romance, Sci-Fi, 1964)
40		Multiplicity (Comedy, Romance, Sci-Fi, 1996)
40		Megamind (Animation, Action, Comedy, Sci-Fi, 2010)
40		Cheech and Chong's Next Movie (Comedy, Crime, Sci-Fi, 1980)
40		Codependent Lesbian Space Alien Seeks Same (Comedy, Romance, Sci-Fi, 2011)
40		I Heart Doomsday (Comedy, Romance, Sci-Fi, 2010)
40		Logan's Run (Action, Adventure, Sci-Fi, 1976)
40		Nutty Professor II: The Klumps (Comedy, Romance, Sci-Fi, 2000)
40		My Super Ex-Girlfriend (Comedy, Romance, Sci-Fi, 2006)
40		Astronomy of Errors (Comedy, Romance, Sci-Fi, 2000)
40		The Invisible Woman (Comedy, Romance, Sci-Fi, 1940)
40		The Mouse on the Moon (Comedy, Romance, Sci-Fi, 1963)
39		Very Close Encounters of the Fourth Kind (Comedy, Sci-Fi, 1978)
39		X-Men (Action, Adventure, Sci-Fi, 2000)
39		Dominant Gene (Action, Adventure, Sci-Fi, 2011)
39		Crank: High Voltage (Action, Crime, Sci-Fi, 2009)
39		D.A.R.Y.L. (Family, Sci-Fi, 1985)
39		Robot Overlords (Action, Adventure, Sci-Fi, 2014)
38		The Roly Poly Man (Comedy, Sci-Fi, 1994)
37		Abbott and Costello Meet the Invisible Man (Comedy, Horror, Sci-Fi, 1951)
37		The Flesh Eaters (Comedy, Horror, Sci-Fi, 1964)
37		Interface (Sci-Fi, Comedy, Horror, 1985)
37		Interplanetary (Comedy, Horror, Sci-Fi, 2008)
37		Repli-Kate (Comedy, Sci-Fi, 2002)
37		Paul (Adventure, Comedy, Sci-Fi, 2011)
35		Demolition Man (Action, Crime, Sci-Fi, 1993)
35		Krrish (Action, Adventure, Romance, Sci-Fi, 2006)
35		The Adventures of Buckaroo Banzai Across the 8th Dimension (Adventure, Comedy, Romance, Sci-Fi, 1984)
35		Teenage Mutant Ninja Turtles: Out of the Shadows (Action, Adventure, Comedy, Sci-Fi, 2016)
35		Space Jam (Animation, Adventure, Comedy, Sci-Fi, 1996)
35		The Boy with the X-Ray Eyes (Adventure, Comedy, Family, Sci-Fi, 1999)
35		Baak bin sing gwan (Action, Comedy, Fantasy, Sci-Fi, 1995)
35		Thunderbirds (Action, Adventure, Comedy, Sci-Fi, 2004)
35		Little Shop of Horrors (Comedy, Horror, Musical, Sci-Fi, 1986)
34		The Amazing Spider-Man 2 (Action, Adventure, Sci-Fi, 2014)
34		Trancers (Action, Sci-Fi, 1984)
34		Back to the Future (Adventure, Comedy, Sci-Fi, 1985)
34		Universal Soldier: The Return (Action, Sci-Fi, 1999)
34		Earth Girls Are Easy (Comedy, Musical, Romance, Sci-Fi, 1988)
34		Wired to Kill (Action, Sci-Fi, 1986)
34		Paycheck (Action, Mystery, Sci-Fi, 2003)
34		The Maze Runner (Action, Mystery, Sci-Fi, 2014)
33		TRON (Action, Adventure, Sci-Fi, 1982)
32		Night of the Comet (Comedy, Horror, Sci-Fi, 1984)
32		Voyage of the Rock Aliens (Musical, Sci-Fi, Comedy, 1984)
32		Hyperspace (Sci-Fi, Comedy, 1984)
32		The Brother from Another Planet (Comedy, Sci-Fi, 1984)
32		Repo Man (Comedy, Crime, Sci-Fi, 1984)
32		The Revenge of the Teenage Vixens from Outer Space (Comedy, Sci-Fi, 1985)
32		The American Way (Comedy, Sci-Fi, 1986)
32		Short Circuit (Comedy, Family, Sci-Fi, 1986)
32		Monster in the Closet (Comedy, Horror, Sci-Fi, 1986)
32		The Trouble with Dick (Comedy, Sci-Fi, 1986)
32		PK (Comedy, Drama, Romance, Sci-Fi, 2014)
32		Star Trek IV: The Voyage Home (Adventure, Comedy, Sci-Fi, 1986)
32		TerrorVision (Comedy, Horror, Sci-Fi, 1986)
32		Fright Show (Horror, Comedy, Sci-Fi, 1985)
32		Strangers in Paradise (Comedy, Musical, Sci-Fi, 1984)
32		Blood Suckers from Outer Space (Comedy, Horror, Sci-Fi, 1984)
32		Big Monster on Campus (Comedy, Horror, Sci-Fi, 2000)
32		The Stuff (Comedy, Horror, Sci-Fi, 1985)
32		UFOria (Comedy, Sci-Fi, 1985)
32		Starman (Romance, Sci-Fi, 1984)
32		Morons from Outer Space (Comedy, Sci-Fi, 1985)
32		Dark Star (Comedy, Sci-Fi, 1974)
32		Now You See Him, Now You Don't (Family, Comedy, Sci-Fi, 1972)
32		Mystery Science Theater 3000: The Movie (Comedy, Sci-Fi, 1996)
31		Amazon Women on the Moon (Comedy, Sci-Fi, 1987)
31		Real Men (Action, Comedy, Sci-Fi, 1987)
31		Bad Taste (Comedy, Horror, Sci-Fi, 1987)
31		Spaceballs (Adventure, Comedy, Sci-Fi, 1987)
31		The Time Guardian (Action, Romance, Sci-Fi, 1987)
31		Project X (Comedy, Drama, Sci-Fi, 1987)
31		Akumulátor 1 (Comedy, Fantasy, Romance, Sci-Fi, 1994)
31		The Iron Giant (Animation, Action, Adventure, Sci-Fi, 1999)
31		The Pink Chiquitas (Comedy, Horror, Sci-Fi, 1987)
31		Interzone (Action, Comedy, Sci-Fi, 1987)
31		King Lear (Comedy, Drama, Sci-Fi, 1987)
31		Return of the Living Dead II (Comedy, Horror, Sci-Fi, 1988)
31		Norman's Awesome Experience (Comedy, Sci-Fi, 1988)
31		As Time Goes by (Comedy, Sci-Fi, 1988)
31		Telling Tales (Comedy, Fantasy, Romance, Sci-Fi, 2015)
31		Purple People Eater (Comedy, Family, Sci-Fi, 1988)
31		It Came from Somewhere Else (Comedy, Sci-Fi, 1988)
31		Sons of Steel (Comedy, Musical, Sci-Fi, 1988)
31		Killer Klowns from Outer Space (Comedy, Horror, Sci-Fi, 1988)
31		The Invisible Kid (Comedy, Sci-Fi, 1988)
31		Return of the Killer Tomatoes! (Comedy, Horror, Sci-Fi, 1988)
31		Critters 2 (Comedy, Horror, Sci-Fi, 1988)
31		Not of This Earth (Comedy, Horror, Sci-Fi, 1988)
31		Hell Comes to Frogtown (Action, Comedy, Sci-Fi, 1988)
31		Eat and Run (Comedy, Sci-Fi, 1987)
31		Human Highway (Comedy, Drama, Sci-Fi, 1982)
31		Britannia Hospital (Comedy, Sci-Fi, 1982)
31		Big Meat Eater (Comedy, Musical, Sci-Fi, 1982)
31		Jekyll and Hyde... Together Again (Sci-Fi, Comedy, Music, 1982)
31		I Was a Zombie for the F.B.I. (Comedy, Sci-Fi, 1982)
31		Xing ji dun tai (Sci-Fi, Comedy, 1983)
31		Illegal Alien (Comedy, Sci-Fi, 1982)
31		Star Wars: Episode VI - Return of the Jedi (Action, Adventure, Fantasy, Sci-Fi, 1983)
31		What's Up, Hideous Sun Demon (Comedy, Sci-Fi, 1983)
30		Modern Problems (Comedy, Fantasy, Sci-Fi, 1981)
30		Meet the Applegates (Comedy, Sci-Fi, 1990)
30		The Age of Insects (Sci-Fi, Comedy, Horror, 1990)
30		Heartbeeps (Sci-Fi, Comedy, 1981)
30		The Spirit of '76 (Comedy, Sci-Fi, 1990)
30		Caveman (Comedy, Sci-Fi, 1981)
30		Simon (Comedy, Sci-Fi, 1980)
30		Goodbye, 20th Century (Adventure, Comedy, Fantasy, Sci-Fi, 1998)
30		Invasion: Stanford 1991 A.D. (Comedy, Sci-Fi, 1990)
30		The Lobster (Comedy, Drama, Romance, Sci-Fi, 2015)
30		The Invisible Boy (Adventure, Comedy, Family, Sci-Fi, 1957)
30		Your Friends Close (Comedy, Drama, Mystery, Sci-Fi, 2013)
30		It Happened in New York (Comedy, Music, Romance, Sci-Fi, 1935)
30		Virtual Sexuality (Comedy, Drama, Romance, Sci-Fi, 1999)
30		The Importance of Being Russell (Comedy, Fantasy, Romance, Sci-Fi, 2006)
30		Earthbound (Family, Sci-Fi, Comedy, 1981)
30		The Incredible Shrinking Woman (Comedy, Sci-Fi, 1981)
30		Bride of Re-Animator (Comedy, Horror, Sci-Fi, 1989)
30		Wooly Booly: Ang classmate kong alien (Comedy, Sci-Fi, 1989)
30		Dr. Caligari (Comedy, Horror, Sci-Fi, 1989)
30		Second Sight (Comedy, Mystery, Sci-Fi, 1989)
30		Tremors (Comedy, Horror, Sci-Fi, 1990)
30		Terminal City Ricochet (Comedy, Sci-Fi, 1990)
30		Spaced Invaders (Adventure, Comedy, Sci-Fi, 1990)
30		Alien Space Avenger (Comedy, Horror, Sci-Fi, 1989)
30		Mutant on the Bounty (Comedy, Sci-Fi, 1989)
30		Lobster Man from Mars (Comedy, Horror, Sci-Fi, 1989)
30		Blood Beach (Comedy, Horror, Sci-Fi, 1980)
30		Meet the Hollowheads (Comedy, Horror, Sci-Fi, 1989)
30		The Return of Swamp Thing (Sci-Fi, Horror, Comedy, 1989)
30		Rising Storm (Action, Comedy, Sci-Fi, 1989)
30		Earthbound (Comedy, Fantasy, Romance, Sci-Fi, 2012)
30		Blast from the Past (Comedy, Drama, Romance, Sci-Fi, 1999)
30		Teknolust (Comedy, Drama, Romance, Sci-Fi, 2002)
30		Comet (Comedy, Drama, Romance, Sci-Fi, 2014)
30		Kaboom (Comedy, Mystery, Romance, Sci-Fi, 2010)
30		Bubble Boy (Adventure, Comedy, Romance, Sci-Fi, 2001)
30		Journey 2: The Mysterious Island (Action, Adventure, Comedy, Sci-Fi, 2012)
30		Griff the Invisible (Comedy, Drama, Romance, Sci-Fi, 2010)
30		Electric Dreams (Comedy, Drama, Music, Sci-Fi, 1984)
30		The Future (Comedy, Drama, Romance, Sci-Fi, 2011)
29		Critters 3 (Comedy, Horror, Sci-Fi, 1991)
29		Where's Willie? (Comedy, Family, Sci-Fi, 1978)
29		Piranha (Comedy, Horror, Sci-Fi, 1978)
29		Cocoon (Sci-Fi, 1985)
29		C.H.O.M.P.S. (Comedy, Family, Sci-Fi, 1979)
29		Rocky Horror Show Live (Comedy, Musical, Sci-Fi, 2015)
29		Class of Nuke 'Em High Part II: Subhumanoid Meltdown (Comedy, Horror, Sci-Fi, 1991)
29		The Borrower (Comedy, Horror, Sci-Fi, 1991)
29		Guyver (Sci-Fi, Action, Comedy, 1991)
29		There's Nothing Out There (Comedy, Horror, Sci-Fi, 1991)
29		Humanoids from Atlantis (Action, Comedy, Sci-Fi, 1992)
29		Hyper Sapien: People from Another Star (Family, Sci-Fi, 1986)
29		Tribulation 99: Alien Anomalies Under America (Comedy, Sci-Fi, 1992)
29		Star Trek: Nemesis (Action, Adventure, Sci-Fi, 2002)
29		Blobermouth (Comedy, Horror, Sci-Fi, 1991)
29		Spaced Out (Comedy, Sci-Fi, 1979)
29		The Cat from Outer Space (Comedy, Family, Sci-Fi, 1978)
29		Transformers (Action, Adventure, Sci-Fi, 2007)
29		The Troops & Aliens (Comedy, Crime, Sci-Fi, 1979)
29		Critters 4 (Comedy, Horror, Sci-Fi, 1992)
29		Suburban Commando (Action, Comedy, Sci-Fi, 1991)
29		Space Case (Comedy, Sci-Fi, 1992)
29		The Truman Show (Comedy, Drama, Sci-Fi, 1998)

Notes: Movies similar to Weird Science, Movies like Weird Science, Comedy, Romance, Sci-Fi, John Hughes, Anthony Michael Hall, Ilan Mitchell-Smith, Kelly LeBrock, Bill Paxton, SF, Science Fiction, SciFi, Sci Fi, Films, Video, Movie Similarities