45		Monuments of Mars (DOS, 1991)
45		Metal Mutant (DOS, 1991)
44		The Game With No Name (DOS, 1990)
43		Obliterator (DOS, 1989)
43		Fire and Ice (DOS, 1989)
43		Alien Worlds (DOS, 1989)
41		Spingun (Windows, 2016)
41		Kurt's Spaced Invaders (DOS, 1995)
41		Invasion of the Mutant Space Bats of Doom (DOS, 1995)
40		Defy Gravity (Windows, 2011)
40		Descension (Windows, 2011)
40		Rocket Lander (DOS, 1982)
40		Round 42 (DOS, 1986)
40		Trancelation (Windows, 2018)
40		Cyril Cyberpunk (DOS, 1996)
40		Cylindrix (DOS, 1996)
40		Monuments of Mars (Windows, 2015)
40		Liberator (Windows, 2010)
40		Atomaders (Windows, 2002)
40		Cylindrix (Windows, 2001)
40		Great Glacier (Windows, 2004)
40		Missile Command (Windows, 1999)
40		TechnoSylph: vsys gaiden Special version (Windows, 2003)
40		Lunar Jetman (Windows, 2003)
40		Beep (Windows, 2011)
40		Exolon DX (Windows, 2005)
40		Plasma Warrior (Windows, 2007)
40		1Key Rocket Launcher (Windows, 2005)
40		Jumper: Redux (Windows, 2005)
40		Jumper! (Windows, 2004)
40		Jetpak: Solar Crisis (Windows, 2004)
40		Space Junkie (Windows, 1997)

Notes: Games similar to Orion Odyssey: The Search for the Magic Ankh, Games like Orion Odyssey: The Search for the Magic Ankh, DOS, Action, Sci-Fi, Futuristic, Arcade, Platform, PC, Game Similarities.