64		Frederik Pohl's Gateway (DOS, 1992)
64		Amazon (DOS, 1984)
63		Gateway II: Homeworld (DOS, 1993)
63		Stationfall (DOS, 1987)
63		Planetfall (DOS, 1983)
62		Starcross (DOS, 1982)
62		Frederik Pohl's Gateway (Windows, 1995)
54		Leather Goddesses of Phobos (DOS, 1986)
53		Rama (Windows, 1996)
52		Rama (DOS, 1996)
51		Universe 3 (DOS, 1989)
50		Captain Gysi: Galaxis Futura (Windows, 1998)
50		Starship Titanic (Windows, 1998)
49		Nine Princes in Amber (DOS, 1985)
48		The Hitchhiker's Guide to the Galaxy (DOS, 1984)
48		Fahrenheit 451 (DOS, 1984)
45		The Adventures of Buckaroo Banzai: Across the Eighth Dimension (DOS, 1985)
45		Star Trek: The Kobayashi Alternative (DOS, 1985)
45		Dopplegänger (DOS, 1985)
44		Star Trek: The Promethean Prophecy (DOS, 1986)
43		Lone Echo (Windows, 2017)
43		Supernova (DOS, 1987)
42		Star Trek: First Contact (DOS, 1988)
42		Alien (DOS, 1982)
42		The Twilight Zone (DOS, 1988)
42		Timequest (DOS, 1991)
42		Guardians of Infinity: To Save Kennedy (DOS, 1988)
42		The Star Portal (DOS, 1988)
41		Space Quest 6: Roger Wilco in the Spinal Frontier (Windows, 1995)
41		Die Höhlenwelt Saga: Der Leuchtende Kristall (DOS, 1994)
41		7 Days a Skeptic (Windows, 2004)
40		Deliver Us the Moon: Fortuna (Windows, 2018)
40		Captain Gysi und das Raumschiff Bonn (DOS, 1997)
40		Las llaves del tiempo (DOS, 1999)
40		Kingdom Without End (DOS, 2001)
40		Doctor Who: The Adventure Games (Windows, 2014)
40		Code 7 (Windows, 2017)
40		Versus: The Elite Trials (Windows, 2016)
40		Demoniak (DOS, 1991)
40		Intergalactic Bar Mans Pub Crawl (DOS, 1991)
40		Projekt Prometheus (DOS, 1991)
40		Space Quest IV.5: Roger Wilco And The Voyage Home (Windows, 2008)
40		Gun Mute (Windows, 2008)
40		Space Quest 6: Roger Wilco in the Spinal Frontier (DOS, 1995)

Notes: Games similar to Rendezvous with Rama, Games like Rendezvous with Rama, Trillium Corp., Trillium Corp., DOS, Adventure, Sci-Fi, Futuristic, Interactive Fiction, Text Adventure, Puzzle elements, Space station, Spaceship, PC, Game Similarities.